Pierre Fabre is the 2nd largest dermo-cosmetics laboratory in the world, the 2nd largest private French pharmaceutical group and the market leader in France for products sold over the counter in pharmacies.

Its portfolio includes several medical franchises and international brands including Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau Thermale Avène, Klorane, Ducray, René Furterer, A-Derma, Naturactive, Pierre Fabre Oral Care. 

Established in the Occitanie region since its creation, and manufacturing over 95% of its products in France, the Group employs some 10,000 people worldwide. Its products are distributed in about 130 countries. 86% of the Pierre Fabre Group is held by the Pierre Fabre Foundation, a government-recognized public-interest foundation, while a smaller share is owned by its employees via an employee stock ownership plan. 

In 2019, Ecocert Environment assessed the Group’s corporate social and environmental responsibility approach in accordance with the ISO 26000 sustainable development standard and awarded it the “Excellence” level.

Pierre Fabre is recognized as one of the "World's Best Employers 2021" by Forbes. Our group is ranked in the Top 3 in the cosmetics industry and in the Top 10 in the pharmaceutical industry worldwide. 

Your mission

We’re looking for a talented and driven PKPD project leader with a strong background in drug development and a passion for innovation to join our dynamic PKPD department. If you thrive in international, cross-functional environments and want to shape the future of therapeutic discovery, we want to hear from you.

As a key scientific leader and member of the core project teams, you will design and implement cutting-edge PKPD, DMPK, and ADME strategies from early discovery through preclinical development. You’ll be the face of the PKPD department in internal and external engagements—collaborating with global experts, regulatory authorities, and strategic partners.

What You’ll Do

• Strategic Leadership: Define PKPD needs across all development stages—from early preclinical to First-in-Human—ensuring alignment on study design, timelines, and budgets.
• Study Oversight: Lead or coordinate in vitro, in vivo, and in silico PK/PKPD studies, whether conducted in-house or outsourced, ensuring scientific rigor and operational excellence.
• Asset Evaluation: Provide expert PKPD assessments of external assets, contributing to strategic decision-making in licensing or acquisition.
• Cross-Functional Collaboration: Work closely with clinicians, statisticians, pharmacologists, toxicologists, and regulatory experts to drive project success.
• Scientific Documentation: Author key sections of regulatory and scientific documents, including study protocols, Investigator’s Brochures (IB), IND/IMPDs, NDAs, PIPs, and Risk Management Plans.
• Global Engagement: Represent the PKPD function in interactions with regulatory bodies, CROs, key opinion leaders, and business partners.

🌍 What You Bring

• Proven experience in PKPD within drug development, ideally in an international setting.
• Strong scientific acumen and ability to translate complex data into actionable insights.
• Excellent communication skills and a collaborative mindset.

This position is compatible with teleworking up to 2 days a week after the trial period.

We offer an attractive remuneration/benefits package: Incentives, profit-sharing, Pierre Fabre shareholding with matching contribution, health and provident insurance, 16 days of holidays (RTT) in addition to 25 days of personal holidays, public transport participation, very attractive CE...

• At least 5 year industry experience in a multicultural English speaking environment, with a solid track record in PK/PKPD drug development
• Practical knowledge and experience of PK/PKPD preclinical and clinical trial design and execution, including data collection, analysis and reporting approaches + filling of regulatory dossiers.
• Previous experience (hands-on) interpretation of PK and PKPD data, with in-silico methods.
• Significant track record with early drug development phases or moving candidate drugs to the clinic.

• Fluency in English, both written and spoken.

We are convinced that diversity is a source of fulfillment, social balance and complementarity for our employees, which is why our offers are open to all, without restriction.